mtor total (Cell Signaling Technology Inc)
Structured Review

Mtor Total, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 8569 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/total-mtor+antibody/mTOR+Antibody/pmc12975357-114-49-54
Average 97 stars, based on 8569 article reviews
Images
1) Product Images from "Amino Acid Signaling in Skeletal Muscle Is Blunted by Prematurity in a Piglet Model"
Article Title: Amino Acid Signaling in Skeletal Muscle Is Blunted by Prematurity in a Piglet Model
Journal: The Journal of Nutrition
doi: 10.1016/j.tjnut.2025.101303
Figure Legend Snippet: Current concepts of multiple amino acid–sensing input to mTORC1. AA, amino acid; Akt, RAC-α serine/threonine-protein kinase; ARF1, ADP-ribosylation factor 1; BCAA, branched-chain amino acid; CASTOR1, cytosolic arginine sensor for mTORC1 subunit 1; GATOR1/2, GAP activity toward RAGs 1/2; LARS, leucine-tRNA-synthase; LAT1/SLC7A5, L-type amino acid transporter 1; mTORC1, mechanistic target of rapamycin complex 1; PI3K, phosphatidylinositol-3-kinase; RAB1A, Ras-related protein Rab-1A; Rag A/B C/D, RAS-related GTP-binding protein A/B C/D; Ragulator, Late endosomal/lysosomal adaptor and MAPK and mTOR activator; Rheb, Ras homolog enriched in brain; SAM, S-adenosyl methionine; SAMTOR, S-adenosylmethionine sensor upstream of mTORC1; SAR1B, secretion-associated Ras-related GTPase 1B; Sestrin1/2, stress response protein 1/2; SLC38A9, solute carrier family 38 member 9; SNAT2, sodium-coupled neutral amino acid transporter 2; TARS2, threonyl-tRNA synthetase 2; TFEB, transcription factor EB; TSC1/2, tuberous sclerosis complex 1/2; V-ATPase, vacuolar H + -ATPase. Created in BioRender. Ramos dos Santos, A.C. (2026) https://BioRender.com/54b947z .
Techniques Used: Activity Assay, Binding Assay
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Article Title: Lower basal and postprandial muscle protein synthesis after 2 weeks single‐leg immobilization in older men: No protective effect of anti‐inflammatory medication Article Snippet: The primary antibodies from Article Title: Rapamycin and mTORC2 inhibition synergistically reduce contraction‐stimulated muscle protein synthesis Article Snippet: Antibodies against total-mTOR (cat#2972), total-Rictor (cat#2114), total-Raptor (cat#2280), phospho-Akt (Thr308, cat#13038), phospho-Akt (Ser473, cat#9271), phospho-Akt1 (Ser473, cat#9018), phospho-Akt2 (Ser474, cat#8599), Article Title: Intermittent Reloading Attenuates Muscle Atrophy through Modulating Akt/mTOR Pathway Article Snippet: MIYAZAKI, M., M. NOGUCHI, and T. TAKEMASA.. Intermittent Reloading Attenuates Muscle Atrophy through Modulating Akt/ mTOR Pathway.. Med. Article Title: Progranulin depletion inhibits proliferation via the transforming growth factor beta/SMAD family member 2 signaling axis in Kasumi-1 cells Article Snippet: Proteins were then transferred to PVDF membrane, which was blocked in 5% skim milk in TBST (Tris buffer saline with 0.1 % v/v Tween-20) at room temperature for 60 min. After washing with TBST buffer, the membrane was incubated with anti-progranulin (kind gift from Dr. Ginette Serrero; A&G Pharmaceutical, MD, USA), phospho-mTOR, total-mTOR, phospho-Akt, total Akt, phospho-ERK, total-ERK, cleaved PARP, caspase-3, Bax, Bcl-2, Article Title: A CCL2/ROS autoregulation loop is critical for cancer-associated fibroblasts-enhanced tumor growth of oral squamous cell carcinoma. 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Article Title: Lower basal and postprandial muscle protein synthesis after 2 weeks single‐leg immobilization in older men: No protective effect of anti‐inflammatory medication Article Snippet: The primary antibodies from Article Title: Rapamycin and mTORC2 inhibition synergistically reduce contraction‐stimulated muscle protein synthesis Article Snippet: Antibodies against total-mTOR (cat#2972), total-Rictor (cat#2114), total-Raptor (cat#2280), phospho-Akt (Thr308, cat#13038), phospho-Akt (Ser473, cat#9271), phospho-Akt1 (Ser473, cat#9018), phospho-Akt2 (Ser474, cat#8599), Article Title: Intermittent Reloading Attenuates Muscle Atrophy through Modulating Akt/mTOR Pathway Article Snippet: MIYAZAKI, M., M. NOGUCHI, and T. TAKEMASA.. Intermittent Reloading Attenuates Muscle Atrophy through Modulating Akt/ mTOR Pathway.. Med. 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Article Title: Progranulin depletion inhibits proliferation via the transforming growth factor beta/SMAD family member 2 signaling axis in Kasumi-1 cells Article Snippet: Proteins were then transferred to PVDF membrane, which was blocked in 5% skim milk in TBST (Tris buffer saline with 0.1 % v/v Tween-20) at room temperature for 60 min. After washing with TBST buffer, the membrane was incubated with anti-progranulin (kind gift from Dr. Ginette Serrero; A&G Pharmaceutical, MD, USA), phospho-mTOR, total-mTOR, phospho-Akt, total Akt, phospho-ERK, total-ERK, cleaved PARP, caspase-3, Bax, Bcl-2, Article Title: A CCL2/ROS autoregulation loop is critical for cancer-associated fibroblasts-enhanced tumor growth of oral squamous cell carcinoma. 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